Propylene Glycol USP Grade

Why Propylene Glycol USP Grade

Propylene Glycol USP Grade at 100% concentration provides an uninhibited, entirely non-toxic heat transfer fluid and chemical intermediate engineered for operations requiring absolute safety compliance. Because this formulation arrives at full strength with zero added water or corrosion inhibitors, facility engineers can custom-dilute the transparent, colorless liquid to achieve the exact freeze protection curve required for their local climate zone. Diluting this 100% base allows operators to maximize specific heat capacity, as pure glycol transfers heat less efficiently than a balanced glycol-water mixture. For industries evaluating heat transfer options, this product delivers the critical food-safe advantage over highly toxic ethylene glycol, ensuring operational continuity in environments where incidental contact with consumables is a risk. With a flash point of 104°C (219.2°F) and high water solubility, it integrates readily into existing aqueous systems while remaining non-flammable under ambient conditions.

Quick Specs

Application Deep-Dives

• Datacenter liquid cooling loops: Pure 100% PG USP is the engineering choice for rear-door heat exchanger and direct-liquid-cooling rigs where operators dial in their own glycol:water ratio (typically 25–40% by volume) to balance freeze protection against pump head and heat capacity. Uninhibited base lets thermal teams pair their own oxidation/corrosion package to the cooling-loop metallurgy.
• Pharmaceutical solvent & tablet excipient: Meets the USP-NF monograph for direct use in oral, topical, and parenteral formulations. Functions as a humectant, plasticizer, and water-miscible solvent for active pharmaceutical ingredients that resist pure aqueous solubilization.
• Food & beverage processing humectant: GRAS-listed (21 CFR 184.1666). Used in dough conditioners, frozen dairy mix, dressings, and flavor carriers where moisture retention and freeze-thaw stability matter. Food-safe profile permits use in chillers serving food-contact equipment.
• HPLC mobile-phase modifier: 99.9 wt% purity with low water content makes USP Grade PG suitable as a viscosity modifier and selectivity tuner in reversed-phase separations. Its low UV cutoff and lack of inhibitor additives keeps detector baselines clean.
• Cosmetic & personal-care formulation: Standard humectant in lotions, serums, deodorants, and color cosmetics. Functions as a coupling agent for fragrance compounds and a freeze-point depressant in water-based formulations shipped through cold-chain logistics.

USP Compliance & Hazard Profile

Every lot ships against the current United States Pharmacopeia (USP-NF) monograph for Propylene Glycol with typical assay 99.9 wt%, water content ≤0.5%, and confirmation against identification A and B tests. A Certificate of Analysis is available on request via our COA portal. Propylene Glycol is GRAS-affirmed by FDA (21 CFR 184.1666) for direct food use and listed in the FDA Inactive Ingredient Database for pharmaceutical formulation. The material is not regulated under DOT 49 CFR; no UN number, no hazard class, no shipping placard required. Standard PPE for industrial handling includes nitrile or neoprene gloves, splash goggles, and a long-sleeve lab coat; full SDS is linked from this PDP.

Spill, Storage & Disposal

Propylene Glycol is fully water-miscible and biodegradable (typical BOD₅ 0.85 g/g; readily biodegradable per OECD 301). Small spills can be absorbed with vermiculite, sand, or commercial spill pads and disposed per local non-hazardous waste regulations; large industrial spills should be diked and recovered into compatible containers, then routed through a permitted aqueous-waste treatment line. Store between 5–30°C in tightly closed HDPE, polypropylene, stainless steel, or unlined carbon steel containers away from strong oxidizers (perchlorates, peroxides, concentrated nitric acid). Shelf life is 24 months from manufacture date in unopened original packaging.

Packaging, Lead Times & Bulk Pricing

Propylene Glycol USP Grade ships from our Taylor, Texas warehouse in containers sized for every operation:

• Lab & bench: 1 quart, 2-quart case, 1 gallon, 4×1 gallon case
• Production: 5 gallon poly pail, 5 gallon carboy
• Bulk: 55 gallon HDPE drum, 4×55 gallon drum pallet
• Tote: 275 gallon IBC, 330 gallon IBC

Standard ground orders ship within 1–2 business days. Drum and IBC orders are shipped via LTL freight; freight quotes are issued within 1 business day of order placement. For pallet-, truckload-, or contract-volume requests, contact our team at sales@alliancechemical.com or request a quote directly from the variant selector above.

When to Choose a Different Grade

• If your facility requires a pre-mixed, food-safe solution ready for immediate deployment in mild climates without the labor and water-quality variables of on-site dilution, choose 30% Propylene Glycol USP Grade.
• If you are managing industrial closed-loop HVAC systems or heavy-duty chillers with no risk of food contact, operations dictate an inhibited propylene glycol blend with aggressive corrosion protection for internal copper, steel, and brass piping.
• If your facility operates in extreme freeze-prone regions and requires immediate top-off fluid, selecting a pre-diluted 40% or 50% concentration ensures stable freeze point depression without the risk of an improper on-site mixture ratio freezing and bursting system lines.

Why Buy Propylene Glycol USP from Alliance Chemical

Alliance Chemical is a Historically Underutilized Business Zone (HUBZone) certified small business and an HWOSB (Historically Underutilized Women-Owned Small Business) supplier under the Department of Defense Small Business program. Our DLA Approved CAGE Code is 1LT50; DUNS 012941063; UEI GW25FCLNJ5E7. We were awarded the DoD Bronze Medal Supplier of Excellence for sustained delivery and quality performance to federal and federally-adjacent customers. Founded in 1998 and shipping from 204 S Edmond St, Taylor, Texas, we maintain an A+ Better Business Bureau rating and supply USP-grade propylene glycol to pharmaceutical contract manufacturers, federal labs, datacenter operators, and the personal-care industry across all 50 states.