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USP Grade · Bulk Supply · Pharma + Cosmetics

USP Grade
Chemical Bulk Supplier

Alliance Chemical supplies USP Grade chemicals in bulk for pharmaceutical, cosmetics, food, and supplement manufacturers. COA per lot, lot-level purity documentation, DLA-approved supplier (CAGE 1LT50), DOT-compliant hazmat shipping to all 50 U.S. states.

USP Pharma Grade
COA Per Lot
Bulk Drum + IBC
50 U.S. States
01

What "USP Grade" actually means

USP Grade (United States Pharmacopeia) is the highest commercial purity standard for chemicals used in pharmaceutical, cosmetic, food, and supplement manufacturing. USP-grade chemicals meet the purity, identity, and quality specifications published in the United States Pharmacopeia and National Formulary (USP-NF).

USP grade is required when:

  • Manufacturing finished pharmaceutical products (FDA-regulated)
  • Producing cosmetics under FDA cosmetic GMP
  • Compounding pharmaceuticals at the retail or hospital level
  • Food and beverage manufacturing requiring food-grade purity
  • Dietary supplement manufacturing under DSHEA
02

USP vs ACS vs Technical Grade — when each is required

  • Technical Grade — industrial cleaning, manufacturing process inputs, water treatment. Purity ~90-95%.
  • ACS Reagent Grade — research laboratories, analytical chemistry, R&D. Meets American Chemical Society specifications. Purity typically 99%+.
  • USP Grade — pharmaceutical, cosmetic, food, supplement manufacturing. Meets USP-NF specifications. Purity 99%+ with identity verification.
  • USP/FCC — food and beverage applications. Meets both USP and Food Chemicals Codex specifications.

Alliance Chemical stocks all four grades for top products. Specify required grade in your quote request.

03

How to verify USP Grade purity

  1. Request the Certificate of Analysis (COA) for the specific lot you're receiving
  2. Confirm the COA references USP-NF specifications for the substance
  3. Check that purity, identity, and applicable limit tests meet USP requirements
  4. Verify lot traceability back to the manufacturer's COA
  5. Confirm container labeling matches the lot ID + grade designation

Every Alliance Chemical USP-grade shipment includes a COA referencing USP-NF specifications and a unique lot ID matching the product detail page.

04

Alliance Chemical's USP-Grade catalog

Top USP-grade chemicals stocked by Alliance:

  • Propylene Glycol USP — cosmetic and pharmaceutical excipient
  • Phosphoric Acid 75% USP — food and pharmaceutical applications
  • Isopropyl Alcohol 70% USP — disinfection and pharmaceutical
  • Ammonium Hydroxide ACS Grade — analytical + pharma intermediates
  • Glycerin USP — pharmaceutical and cosmetic excipient (on request)
  • Citric Acid USP/FCC — food, beverage, supplement (on request)

Don't see what you need? Request a quote — our catalog includes 200+ chemicals with USP grade available for most.

05

Bulk shipping for pharma and cosmetics buyers

USP-grade chemicals from Alliance ship in:

  • Quart and gallon containers — laboratory + compounding pharmacy
  • Pails (5-gal) — cosmetic manufacturers, small-batch pharma
  • Drums (55-gal) — production-scale pharma + cosmetic, supplement
  • IBC totes (275-330 gal) — large-volume manufacturing

DOT 49 CFR 172.704 hazmat-certified shipper. All 50 U.S. states. COA, SDS, and TSCA documentation delivered with every order.

07

Frequently Asked Questions

What's the difference between USP and USP/FCC grade? +
USP grade meets United States Pharmacopeia specifications. USP/FCC additionally meets Food Chemicals Codex specifications, qualifying the chemical for food and beverage applications.
Does Alliance provide USP COAs with every shipment? +
Yes. Every USP-grade shipment includes a lot-specific COA referencing USP-NF specifications. The COA is matched to the lot ID on the container labels.
Can Alliance handle large-volume pharma manufacturing orders? +
Yes. We ship USP-grade chemicals in drums and IBC totes (275-330 gallons). Federal credentialing (CAGE 1LT50) simplifies procurement for federally-funded pharma research and manufacturing.
Do you support FDA inspection documentation requirements? +
Yes. We provide supplier statements, lot-traceable COAs, and TSCA documentation as needed for FDA inspections of pharmaceutical, cosmetic, and food manufacturers.

Need USP-Grade chemicals in bulk?

COA per lot, lot traceability, drum and IBC available. DLA-approved supplier (CAGE 1LT50). DOT hazmat-certified shipping to all 50 states.

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