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Chemical Comparison

Glycerin vs Propylene Glycol

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Comprehensive comparison of Glycerin and Propylene Glycol including physical properties, applications, safety considerations, and pricing. Alliance Chemical supplies both chemicals in various grades and concentrations.

Quick Comparison Summary

Glycerin

CAS:
56-81-5
Formula:
C₃H₈O₃
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VS

Propylene Glycol

CAS:
57-55-6
Formula:
C₃H₈O₂
Available:
50%, 40%, 30%
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Physical Properties

Physical & Chemical Properties Comparison

Property Glycerin Propylene Glycol Key Difference
Boiling Point 290 °C 188.2°C Glycerin boils 101.8°C higher
Flash Point ⚠️ 177 °C 99°C Propylene Glycol is more flammable
Density 1.261 g/cm³ 1.036 g/cm³ Glycerin is denser
Water Solubility Miscible with water Miscible with water Both fully water soluble
pH 5.5 - 8.0 (10% solution) 6.0-8.0 (50% aqueous solution) Similar pH range
Molecular Weight 92.09 g/mol 76.09 g/mol Glycerin is heavier molecule
Melting Point 17.8 °C -59°C Glycerin melts 76.8°C higher
Vapor Pressure 0.00016 mmHg at 25°C 0.13 mmHg at 20°C Propylene Glycol is more volatile
Auto-ignition Temp ⚠️ 370 °C 371°C Glycerin auto-ignites at lower temp
Vapor Density 3.17 (air = 1) 2.62 (air = 1) Glycerin vapors sink more
Appearance Clear, colorless, viscous liquid Clear, colorless, viscous liquid Similar appearance
Odor Odorless Slightly sweet

Data sourced from PubChem (NIH), OSHA Technical Guidelines, and Alliance Chemical laboratory analysis. Last verified March 2026.

Applications

Applications & Use Cases

Glycerin Best For:

  • Humectant
  • Plasticizer
  • Pharmaceutical excipient
  • Cosmetic ingredient
  • Antifreeze

Propylene Glycol Best For:

  • Industrial solvent
  • Antifreeze
  • Humectant
  • Chemical intermediate
  • Heat transfer fluid

Choosing Between Them

The right choice depends on your specific application, required purity, and handling capabilities. Contact our team for guidance on which chemical best fits your needs.

Safety

Safety & Handling Comparison

Storage Requirements

Always store in original containers in a cool, well-ventilated area per NFPA 30 guidelines. Refer to each product's SDS for specific storage temperature ranges and incompatible materials.

PPE Requirements

At minimum: chemical-resistant gloves, safety goggles, and adequate ventilation per OSHA 29 CFR 1910.132-138. Check each SDS below for chemical-specific PPE requirements.

Fire Hazard

Propylene Glycol has a lower flash point and requires extra fire precautions.

Recommendation

Which Chemical Should You Choose?

Decision Snapshot

Decision Factor Better Fit Why
Evaporation Profile Propylene Glycol Lower boiling point supports faster flash-off.
Fire Safety Margin Glycerin Higher flash point generally reduces ignition risk in handling and storage.
Application Breadth Propylene Glycol Compares distinct listed use cases to avoid generic recommendations.
Purity Flexibility Standard grades Based on availability of 99%+ concentration options in current product metadata.

Choose Glycerin if:

  • You specifically need support for plasticizer applications.
  • You specifically need support for pharmaceutical excipient applications.
  • You need a higher-boiling solvent that stays in-process longer.
  • Fire-risk controls are a priority and you prefer the higher flash-point option.

Choose Propylene Glycol if:

  • You specifically need support for industrial solvent applications.
  • You specifically need support for heat transfer fluid applications.
  • You want a faster-evaporating solvent for quick-dry production steps.
  • You can manage stricter flammable-liquid controls for lower flash-point performance.

Commercial & Fulfillment Snapshot

Built for purchasing teams that need predictable dispatch, compliant documentation, and freight flexibility from parcel to full truckload.

Procurement Advantage Glycerin Propylene Glycol
Grade & Concentration Coverage multiple concentration options by application with industrial/lab procurement support. 50% to 30% with industrial/lab procurement support.
Packaging Depth small packs through bulk freight quantities for parcel, pallet, and truckload planning. small packs through bulk freight quantities for parcel, pallet, and truckload planning.
Dispatch SLA Order by 1 PM CT (Mon-Thu) or noon CT Friday for same-business-day outbound from Taylor, TX. Order by 1 PM CT (Mon-Thu) or noon CT Friday for same-business-day outbound from Taylor, TX.
Freight Optionality UPS Ground for small packs plus LTL/FTL lanes through ABF, SEFL, Saia, XPO, and partner carriers. UPS Ground for small packs plus LTL/FTL lanes through ABF, SEFL, Saia, XPO, and partner carriers.
Compliance Readiness SDS ready now; COA/TDS support available pre-PO and post-order. SDS ready now; COA/TDS support available pre-PO and post-order.
Bulk Procurement CTA Request bulk quote or call (512) 365-6838. Request bulk quote or call (512) 365-6838.

Need Help Deciding? Our technical team can help you choose the right chemical for your specific application. Email sales@alliancechemical.com for expert guidance.

Andre T.

Technical Director, Alliance Chemical

Andre has over 20 years of experience in industrial chemical distribution, helping 10,000+ customers select the right chemicals for applications across manufacturing, water treatment, semiconductor, and laboratory sectors. He specializes in solvent selection, chemical safety compliance, and grade specification.

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Alliance Chemical supplies both Glycerin and Propylene Glycol in various grades and package sizes.

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