60/40 Methanol/DI Water Solution ACS Grade

Product Overview

Alliance Chemical provides ACS Grade 60/40 Methanol/DI Water Solution, a precisely formulated binary solvent system designed for analytical and preparative workflows. This 60/40 v/v mixture of Methanol (Methyl Alcohol, MeOH) and Deionized Water offers a balanced polarity essential for reversed-phase chromatographic separations and UV-transparent performance below 205 nm.

Engineered for consistency, this solution eliminates the variability and labor associated with manual mixing in the laboratory. It is prepared to ACS Reagent Grade standards, ensuring strict control over acidity, residue, and trace impurities. This ready-to-use solvent supports high-purity requirements in pharmaceutical processing, chemical synthesis, and rigorous testing environments.

Key Properties

• Chemical Formula: CH₃OH / H₂O (60/40 v/v)
• Grade: ACS Reagent Grade
• Appearance: Clear, colorless liquid
• Boiling Point: Approx. 64.7°C (Methanol component)
• Density (25°C): 0.787 g/mL
• Refractive Index (20°C): 1.3288
• Flash Point: 11°C (Closed Cup)
• Odor: Slightly sweet / alcohol-like
• Solubility: Miscible in water and many organic solvents

Common Applications

• HPLC Mobile Phase: Primary application in reversed-phase High-Performance Liquid Chromatography (HPLC) for separating organic compounds with reproducible retention times.
• Spectroscopy: Utilized as a baseline solvent for UV-Vis measurements due to low UV cutoff and minimal background interference.
• Pharmaceutical Extraction: Employed in liquid-liquid extraction processes for isolating intermediates requiring specific polarity adjustments.
• Chemical Synthesis: Functions as a reaction medium and participant in organic synthesis workflows.
• Laboratory Cleaning: Effective for rinsing and degreasing sensitive laboratory glassware and equipment.

Safety Precautions

This product is a Flammable Liquid and Toxic. It must be handled in well-ventilated areas, preferably under a fume hood, away from heat, sparks, and open flames. Store in a cool, dry place in tightly closed HDPE or glass containers.

Personal Protective Equipment (PPE): Wear chemical-resistant gloves, safety goggles, and protective clothing. Avoid breathing vapors. Methanol is toxic if swallowed, inhaled, or absorbed through the skin. Refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.

Benefits

• Ready-to-Use: Pre-mixed 60/40 ratio saves laboratory time and reduces human error in solvent preparation.
• ACS Compliant: Meets strict specifications for purity, ensuring reliability in regulatory-aligned workflows.
• UV Transparency: Low impurity profile minimizes baseline noise in sensitive UV-Vis detection methods.

Related Products

• 60/40 Methanol/DI Water Solution (Standard)
• A-A-59601E Type III
• A-A-59601E Type III ACS Grade