Propylene Glycol 40% – USP Grade (C3H8O2)

Category : Glycols

$22.00
Quantity
Size:
Variation:
Other Grades & Concentrations

Available in other grades and concentrations:

CAS: 57-55-6 C3H8O2
Propylene Glycol USP Grade
From $26.45
CAS: 57-55-6 C3H8O2
Propylene Glycol 60% USP Grade
From $19.00
CAS: 57-55-6 C3H8O2
CAS: 57-55-6 50% C3H8O2 / 50% H2O
$22.00
Other Grades & Concentrations

Available in other grades and concentrations:

CAS: 57-55-6 C3H8O2
Propylene Glycol USP Grade
From $26.45
CAS: 57-55-6 C3H8O2
Propylene Glycol 60% USP Grade
From $19.00
CAS: 57-55-6 C3H8O2
CAS: 57-55-6 50% C3H8O2 / 50% H2O

Propylene Glycol 40% – USP Grade (C3H8O2)

$22.00

Commercial Fulfillment Snapshot

Buy Propylene Glycol 40% – USP Grade (C3H8O2) with faster decisions and fewer back-and-forth emails.

Ships from Taylor, Texas. In-stock orders placed before 1:00 PM CT (Mon-Thu) and before 12:00 PM CT (Fri) typically ship same business day. Order online 24/7.

Technical Documents

Lot-specific COA is issued per shipment batch.

Who Buys This
  • Pharmaceutical manufacturers
  • Medical device companies
  • HVAC system operators
  • Food processing facilities
  • Research laboratories
Purity / Grade Guide
  • USP grade pharmaceutical applications
  • Medical & healthcare formulations
  • Regulated industry compliance
  • 40% concentration ready-to-use
Pack Sizes
  • 1 Quart: lab & small jobs
  • 1 Gallon: shop & maintenance
  • 5 Gallon: production & regular use
  • 15 Gallon: mid-volume operations
  • 55 Gallon: bulk drum
  • 275 Gallon: high-volume tote
  • 330 Gallon: max-volume tote
SDS / COA / TDS
  • SDS
  • COA
  • Non-regulated ground shipment
  • USP grade documentation
Small Packs: UPS Ground nationwide for pints, quarts, and gallons.
LTL / FTL: ABF, SEFL, Saia, XPO, and partner carriers for pails, drums, totes, and full truckloads.
Support: Email or call for freight options, hazardous-material routing, and lead-time confirmation.

Why Propylene Glycol 40% – USP Grade

Propylene Glycol 40% – USP Grade delivers reliable freeze and burst protection for operational environments requiring a non-toxic, highly pure thermal fluid. Arriving pre-mixed to an exact 40 percent concentration with purified water, this solution eliminates the labor, scaling risks, and inconsistencies associated with on-site dilution. This specific uninhibited formulation is critical for direct or incidental food, pharmaceutical, and medical contact applications. It ensures strict regulatory compliance while maintaining optimal pumpability and heat transfer efficiency in freezing climates. Unlike ethylene glycol, which is highly toxic and strictly prohibited in consumption-adjacent environments, this USP-grade propylene glycol provides absolute safety without sacrificing thermal performance. Facilities relying on this 40 percent ratio benefit from a balanced freeze protection curve, safeguarding expensive infrastructure and piping during significant temperature drops while avoiding the heavy viscosity drag found in higher concentration fluids.

Best Applications for This Grade

  • Secondary cooling loops and chillers commonly applied in food processing plants, breweries, and dairies, where engineers require a completely non-toxic, USP-compliant fluid to guarantee consumer safety in the event of incidental contact or system leaks.
  • Thermal control systems commonly applied in pharmaceutical manufacturing and medical device temperature regulation, providing stable, reliable thermal dynamics without introducing hazardous chemicals into highly cleaning production zones.
  • Liquid cooling networks commonly applied in AI infrastructure and enterprise datacenters, where facility operators prioritize non-toxic, high-purity thermal fluids to protect sensitive server environments, cooling manifolds, and operational personnel.
  • Heat transfer circuits commonly applied in commercial HVAC systems and solar thermal arrays, delivering effective sub-zero freeze protection and stable flow rates without the environmental and toxicity risks associated with traditional industrial fluids.

When to Choose a Different Grade

  • If your geographic climate is milder and your system prioritizes maximum heat transfer efficiency with a lower fluid viscosity, choose 30% Propylene Glycol USP Grade to reduce the workload on your facility's pumps.
  • If your closed-loop industrial HVAC system consists of multiple mixed metals, operates entirely outside of food-safe zones, and requires built-in chemical corrosion protection, choose 40% Propylene Glycol Inhibited.
  • If your non-food facility operates in extreme sub-zero temperatures and requires a more aggressive freeze protection curve with heavy-duty corrosion resistance, choose 50% Propylene Glycol Inhibited to prevent catastrophic pipe bursts.
Property Value
Molecular Weight 76.09
Formula C3H8O2
Assay 39-41%
Grade USP Grade
Flash Point Not applicable (aqueous solution; not classified as flammable)
Form Liquid
Solubility Miscible with water and many organic solvents
Appearance Clear, colorless liquid
Melting Point -59
Boiling Point 188.2
Specific Gravity 1.036
Industry Analytical Chemistry, Pharmaceutical, Food Industry, Cosmetics, Industrial

Frequently Asked Questions About Propylene Glycol 40% – USP Grade (C3H8O2)

What is Propylene Glycol 40% – USP Grade (C3H8O2) and what is its chemical formula?
Propylene Glycol 40% – USP Grade (C3H8O2) is a chemical compound with the molecular formula C3H8O2, registered under CAS Number 57-55-6 by the Chemical Abstracts Service (PubChem), with a molecular weight of 76.09 g/mol. Alliance Chemical supplies Propylene Glycol 40% – USP Grade (C3H8O2) in USP grade for laboratory, industrial, and commercial applications.
What are the physical properties of Propylene Glycol 40% – USP Grade (C3H8O2)?
According to the NIOSH Pocket Guide to Chemical Hazards, Propylene Glycol 40% – USP Grade (C3H8O2) is supplied as a clear, colorless, slightly viscous liquid.. It has a boiling point of 188°C (pure component reference)°C, a flash point of Not applicable (aqueous solution; not classified as flammable). The specific gravity is 1.032 relative to water. Solubility: Fully miscible with water and many organic solvents.
What grade and purity of Propylene Glycol 40% – USP Grade (C3H8O2) does Alliance Chemical offer?
Alliance Chemical offers Propylene Glycol 40% – USP Grade (C3H8O2) in USP grade with a purity assay of 40%. Every lot ships with a Certificate of Analysis (COA) and Safety Data Sheet (SDS) prepared in accordance with OSHA Hazard Communication Standard 29 CFR 1910.1200 and GHS Revision 7. Download SDS.
What are common industrial applications of Propylene Glycol 40% – USP Grade (C3H8O2)?
Propylene Glycol 40% – USP Grade (C3H8O2) serves a wide range of sectors, including Food & Agriculture, HVAC & Cooling, Healthcare & Pharma, and Industrial & Manufacturing.Alliance Chemical provides the documentation and quality certifications required for use in regulated environments.
What PPE is required when handling Propylene Glycol 40% – USP Grade (C3H8O2)?
OSHA-mandated PPE per 29 CFR 1910.132-138:Nitrile gloves (8+ mil), safety goggles, flame-resistant clothing, grounded footwear, closed-toe chemical-resistant footwear. Respiratory protection (organic vapor cartridge) required in areas exceeding PEL/TLV per 29 CFR 1910.134. Emergency eyewash station and safety shower must be accessible within 10 seconds per ANSI Z358.1. Consult the SDS available from Alliance Chemical for complete PPE requirements.
What are the storage requirements for Propylene Glycol 40% – USP Grade (C3H8O2)?
Store perOSHA 29 CFR 1910.106: Approved flammable storage cabinet, maximum 60 gallons per cabinet, grounding/bonding required. Temperature range:15-25°C. Segregate from:oxidizers, ignition sources. Maximum storage:2-3 years unopened.
What is the emergency spill procedure for Propylene Glycol 40% – USP Grade (C3H8O2)?
Emergency response per EPA SPCC (40 CFR 112) and OSHA 29 CFR 1910.120: (1) Alert personnel, evacuate area to 100 feet. (2) Eliminate ignition sources if flammable. (3) Don PPE per SDS Section 8. (4) Stop leak if safe; use emergency shutoffs. (5) Contain with non-combustible absorbent materials, dike with sand/earth. (6)Absorb with vermiculite or commercial spill kits. (7) Collect in DOT-approved containers, label as hazardous waste. Check 40 CFR 302.4 for Reportable Quantity. Emergency: Chemtel 1-800-255-3924 (24/7). Non-emergency: Alliance Chemical 512-365-6838.
What is the DOT shipping classification for Propylene Glycol 40% – USP Grade (C3H8O2)?
DOT Classification per 49 CFR 172.101:UN1993 (Flammable Liquid, N.O.S.), Hazard Class3 (Flammable), Packing GroupII/III. Requires: Hazmat shipping papers (49 CFR 172.200), UN specification packaging (49 CFR 173), hazmat labels (172.400). Alliance Chemical ships all orders in DOT-compliant packaging with proper documentation.
How must Propylene Glycol 40% – USP Grade (C3H8O2) waste be disposed?
Disposal per RCRA (40 CFR 261-265):Characteristic waste D001 (Ignitable, flash point <60°C). Generator requirements: EPA ID number required if >100 kg/month (40 CFR 262.12). Use EPA-permitted Treatment, Storage, Disposal Facility (TSDF). Never discharge to sewer without POTW written approval (40 CFR 403). Container disposal: Triple rinse (40 CFR 261.7), offer for reconditioning/recycling. State regulations may be more stringent — check with your local environmental agency. Consult the Alliance Chemical SDS for product-specific disposal guidance.
Does Alliance Chemical provide an SDS and COA for Propylene Glycol 40% – USP Grade (C3H8O2)?
Yes. Alliance Chemical provides a Safety Data Sheet (SDS) and Certificate of Analysis (COA) for every lot of Propylene Glycol 40% – USP Grade (C3H8O2). The SDS is prepared in accordance with OSHA Hazard Communication Standard 29 CFR 1910.1200 and the Globally Harmonized System (GHS) Revision 7, covering all 16 required sections including hazard identification, first aid measures, firefighting measures, handling and storage, exposure controls, and regulatory information. The SDS is available for download directly from this product page. COAs are available upon request by contacting Alliance Chemical at 512-365-6838.