40% Propylene Glycol — USP Grade

Name: Propylene Glycol 40% – USP Grade (C3H8O2)
Brand: Alliance Chemical
SKU: BHS-3V7-816
Availability: InStock

Commercial Fulfillment Snapshot

Buy Propylene Glycol 40% – USP Grade (C3H8O2) with faster decisions and fewer back-and-forth emails.

Ships from Taylor, Texas. In-stock orders placed before 1:00 PM CT (Mon-Thu) and before 12:00 PM CT (Fri) typically ship same business day. Order online 24/7.

Email Bulk Quote Call (512) 365-6838

Technical Documents

SDS TDS COA

Lot-specific COA is issued per shipment batch.

Who Buys This

Pharmaceutical manufacturers
Medical device companies
HVAC system operators
Food processing facilities
Research laboratories

Purity / Grade Guide

USP grade pharmaceutical applications
Medical & healthcare formulations
Regulated industry compliance
40% concentration ready-to-use

Pack Sizes

1 Quart: lab & small jobs
1 Gallon: shop & maintenance
5 Gallon: production & regular use
15 Gallon: mid-volume operations
55 Gallon: bulk drum
275 Gallon: high-volume tote
330 Gallon: max-volume tote

SDS / COA / TDS

SDS
COA
Non-regulated ground shipment
USP grade documentation

Small Packs: UPS Ground nationwide for pints, quarts, and gallons.

LTL / FTL: ABF, SEFL, Saia, XPO, and partner carriers for pails, drums, totes, and full truckloads.

Support: Email or call for freight options, hazardous-material routing, and lead-time confirmation.

Description
Product Documents
Chemical Profile

Product Overview

Propylene Glycol 40% – USP Grade (C₃H₈O₂) is a clear, colorless liquid solution composed of high-purity propylene glycol and deionized water. Also known in the industry as Propane-1,2-diol, PG, or MPG, this USP-grade material meets strict pharmaceutical standards, delivering reliable solvent properties and low toxicity. The ±1% assay range (39–41% w/w) is verified by titration, ensuring consistent carrier performance for pharmaceutical excipients, food processing, and industrial manufacturing.

This solution serves as an essential solvent, humectant, and carrier due to its complete miscibility with water and many organic solvents. With a typical APHA color of 5 and low residue after ignition, it is ideal for sensitive applications requiring high purity. The material is packaged under controlled conditions to strictly limit moisture uptake and is verified against ACS/USP testing protocols to ensure compliance with USP-NF Monograph standards.

Key Properties

Appearance: Clear, colorless liquid
Grade: USP (United States Pharmacopeia)
CAS Number: 57-55-6
Formula: C₃H₈O₂
Assay (Wt %): 39–41% (Typical 40%)
Specific Gravity (25°C): 1.036–1.041
Boiling Point: 188.2°C (Pure component base)
Solubility: Miscible with water and many organic solvents
Residue After Ignition: Max 0.005%
Chlorides/Sulfates: Strictly controlled to PPM levels
Heavy Metals (as Pb): Max 0.2 ppm

Common Applications

Pharmaceutical Excipients: Serves as a solvent and carrier for active ingredients, meeting USP-grade purity requirements.
Industrial Heat Transfer: Used in antifreeze and heat transfer fluids where low toxicity and specific thermal properties are required.
Cosmetic Formulations: Acts as a humectant and moisturizing solvent in personal care products.
Processing Solvent: Effective medium for synthesis and purification steps requiring a polar, water-miscible solvent.
Analytical Chemistry: Used as a mobile phase component in chromatography workflows.
Food Processing: Functions as a humectant and stabilizer in various food-grade applications.

Safety and Handling

Store in a cool, dry place away from direct sunlight, ensuring containers (HDPE or glass) are tightly sealed to prevent contamination. While Propylene Glycol 40% is generally considered low toxicity, standard industrial hygiene practices should be observed. Wear appropriate PPE, including gloves and safety goggles, when handling bulk quantities. Ensure adequate ventilation in processing areas.

This product is not classified as a hazardous material for transport. However, always refer to the Safety Data Sheet (SDS) for detailed handling, spill, and emergency response procedures.

Benefits

USP-Grade Compliance – Rigorously tested to meet USP-NF Monograph requirements for assay and impurities.
Versatile Performance – Excellent solubility and stability for use as a solvent, carrier, or humectant.
High Purity Profile – Low heavy metal and chloride content ensures compatibility with sensitive formulations.

Related Products

Property	Value
Molecular Weight	76.09 g/mol
Formula	C3H8O2
Assay	40%
Grade	USP
Flash Point	Not applicable (aqueous solution; not classified as flammable)
Form	Liquid
Solubility	Fully miscible with water and many organic solvents
Appearance	Clear, colorless, slightly viscous liquid
Boiling Point	188°C (pure component reference) °C
Specific Gravity	1.032
Industry	Datacenter , HVAC , Food Processing, Pharmaceutical , Industrial , AI Infrastructure, Medical , Solar Thermal

Frequently Asked Questions About Propylene Glycol 40% – USP Grade (C3H8O2)

What is Propylene Glycol 40% – USP Grade (C3H8O2) and what is its chemical formula?

Propylene Glycol 40% – USP Grade (C3H8O2) is a chemical compound with the molecular formula C3H8O2, registered under CAS Number 57-55-6 by the Chemical Abstracts Service (PubChem), with a molecular weight of 76.09 g/mol. Alliance Chemical supplies Propylene Glycol 40% – USP Grade (C3H8O2) in USP grade for laboratory, industrial, and commercial applications.

What are the physical properties of Propylene Glycol 40% – USP Grade (C3H8O2)?

According to the NIOSH Pocket Guide to Chemical Hazards, Propylene Glycol 40% – USP Grade (C3H8O2) is supplied as a clear, colorless, slightly viscous liquid.. It has a boiling point of 188°C (pure component reference)°C, a flash point of Not applicable (aqueous solution; not classified as flammable). The specific gravity is 1.032 relative to water. Solubility: Fully miscible with water and many organic solvents.

What grade and purity of Propylene Glycol 40% – USP Grade (C3H8O2) does Alliance Chemical offer?

Alliance Chemical offers Propylene Glycol 40% – USP Grade (C3H8O2) in USP grade with a purity assay of 40%. Every lot ships with a Certificate of Analysis (COA) and Safety Data Sheet (SDS) prepared in accordance with OSHA Hazard Communication Standard 29 CFR 1910.1200 and GHS Revision 7. Download SDS.

What are common industrial applications of Propylene Glycol 40% – USP Grade (C3H8O2)?

Propylene Glycol 40% – USP Grade (C3H8O2) serves a wide range of sectors, including Datacenter, HVAC, Food Processing, Pharmaceutical, Industrial, and AI Infrastructure, among others.Alliance Chemical provides the documentation and quality certifications required for use in regulated environments.

What PPE is required when handling Propylene Glycol 40% – USP Grade (C3H8O2)?

OSHA-mandated PPE per 29 CFR 1910.132-138:Nitrile gloves (8+ mil), safety goggles, flame-resistant clothing, grounded footwear, closed-toe chemical-resistant footwear. Respiratory protection (organic vapor cartridge) required in areas exceeding PEL/TLV per 29 CFR 1910.134. Emergency eyewash station and safety shower must be accessible within 10 seconds per ANSI Z358.1. Consult the SDS available from Alliance Chemical for complete PPE requirements.

What are the storage requirements for Propylene Glycol 40% – USP Grade (C3H8O2)?

Store perOSHA 29 CFR 1910.106: Approved flammable storage cabinet, maximum 60 gallons per cabinet, grounding/bonding required. Temperature range:15-25°C. Segregate from:oxidizers, ignition sources. Maximum storage:2-3 years unopened.

What is the emergency spill procedure for Propylene Glycol 40% – USP Grade (C3H8O2)?

Emergency response per EPA SPCC (40 CFR 112) and OSHA 29 CFR 1910.120: (1) Alert personnel, evacuate area to 100 feet. (2) Eliminate ignition sources if flammable. (3) Don PPE per SDS Section 8. (4) Stop leak if safe; use emergency shutoffs. (5) Contain with non-combustible absorbent materials, dike with sand/earth. (6)Absorb with vermiculite or commercial spill kits. (7) Collect in DOT-approved containers, label as hazardous waste. Check 40 CFR 302.4 for Reportable Quantity. Emergency: Chemtel 1-800-255-3924 (24/7). Non-emergency: Alliance Chemical 512-365-6838.

What is the DOT shipping classification for Propylene Glycol 40% – USP Grade (C3H8O2)?

DOT Classification per 49 CFR 172.101:UN1993 (Flammable Liquid, N.O.S.), Hazard Class3 (Flammable), Packing GroupII/III. Requires: Hazmat shipping papers (49 CFR 172.200), UN specification packaging (49 CFR 173), hazmat labels (172.400). Alliance Chemical ships all orders in DOT-compliant packaging with proper documentation.

How must Propylene Glycol 40% – USP Grade (C3H8O2) waste be disposed?

Disposal per RCRA (40 CFR 261-265):Characteristic waste D001 (Ignitable, flash point <60°C). Generator requirements: EPA ID number required if >100 kg/month (40 CFR 262.12). Use EPA-permitted Treatment, Storage, Disposal Facility (TSDF). Never discharge to sewer without POTW written approval (40 CFR 403). Container disposal: Triple rinse (40 CFR 261.7), offer for reconditioning/recycling. State regulations may be more stringent — check with your local environmental agency. Consult the Alliance Chemical SDS for product-specific disposal guidance.

Does Alliance Chemical provide an SDS and COA for Propylene Glycol 40% – USP Grade (C3H8O2)?

Yes. Alliance Chemical provides a Safety Data Sheet (SDS) and Certificate of Analysis (COA) for every lot of Propylene Glycol 40% – USP Grade (C3H8O2). The SDS is prepared in accordance with OSHA Hazard Communication Standard 29 CFR 1910.1200 and the Globally Harmonized System (GHS) Revision 7, covering all 16 required sections including hazard identification, first aid measures, firefighting measures, handling and storage, exposure controls, and regulatory information. The SDS is available for download directly from this product page. COAs are available upon request by contacting Alliance Chemical at 512-365-6838.