Propylene Glycol USP Grade

Name: Propylene Glycol USP Grade
Brand: Alliance Chemical
SKU: F2N-3WG-98L
Availability: InStock
Rating: 5.0 (2 reviews)

Commercial Fulfillment Snapshot

Buy Propylene Glycol USP Grade with faster decisions and fewer back-and-forth emails.

Ships from Taylor, Texas. In-stock orders placed before 1:00 PM CT (Mon-Thu) and before 12:00 PM CT (Fri) typically ship same business day. Order online 24/7.

Email Bulk Quote Call (512) 365-6838

Technical Documents

SDS TDS COA

Lot-specific COA is issued per shipment batch.

Who Buys This

Pharmaceutical manufacturers
Medical device companies
Cosmetic formulators
Personal care manufacturers
Research laboratories

Purity / Grade Guide

USP pharmaceutical grade quality
Medical & cosmetic formulations
Regulated industry applications
COA confirms grade compliance

Pack Sizes

1 Quart: lab & small jobs
1 Gallon: shop & maintenance
5 Gallon: production & regular use
15 Gallon: mid-volume operations
55 Gallon: bulk drum
275 Gallon: high-volume tote
330 Gallon: max-volume tote

SDS / COA / TDS

SDS safety documentation included
COA certificate of analysis
USP grade verification
Non-regulated ground shipment

Small Packs: UPS Ground nationwide for pints, quarts, and gallons.

LTL / FTL: ABF, SEFL, Saia, XPO, and partner carriers for pails, drums, totes, and full truckloads.

Support: Email or call for freight options, hazardous-material routing, and lead-time confirmation.

Description
Product Documents
Chemical Profile

Product Overview

Propylene Glycol USP Grade is a high-purity, colorless, odorless, and hygroscopic liquid extensively used as a solvent and humectant in industrial, pharmaceutical, and food processing applications. Also known as Propane-1,2-diol, MPG, or simply PG, this chemical possesses a formula of C₃H₈O₂. It acts as a diol, providing necessary miscibility with water and organic solvents. This product strictly adheres to USP-NF Monograph standards, ensuring full traceability to pharmacopeial specifications and consistent quality across all production lots.

With a typical assay of 99.9 wt%, Alliance Chemical guarantees stringent control of impurities, including chlorides, nitrates, and heavy metals. This USP Grade Propylene Glycol is engineered for stability, exhibiting a controlled vapor pressure profile and low residue on ignition. It is fully compatible with HDPE and glass storage. Its low toxicity profile and low vapor emissions make it the preferred choice for sensitive environments, serving as a critical component in HPLC mobile phases, non-toxic antifreeze systems, and cosmetic formulations.

Key Properties

Assay (wt%): 99.5–100.5 (Typical: 99.9)
Chemical Formula: C₃H₈O₂
CAS Number: 57-55-6
Molecular Weight: 76.09 g/mol
Boiling Point: 188.2°C
Specific Gravity (20°C): 1.033–1.039
Water Content: <0.5% (Typical: 0.1%)
Flash Point: 97°C
Appearance: Clear, colorless liquid
Grade: USP (United States Pharmacopeia)

Common Applications

Industrial Heat Transfer: Utilized as a non-toxic antifreeze and de-icing agent for industrial cooling systems requiring low toxicity profiles.
Pharmaceutical Solvent: Serves as a primary solvent and carrier in drug formulations, meeting strict USP compliance for purity.
Food Processing Humectant: Acts as a moisture-retaining agent to preserve texture and prevent crystallization in food products.
HPLC Mobile Phase: Used in reversed-phase chromatography for the separation of organic compounds in analytical laboratories.
Cosmetic Formulations: Functions as a moisturizer, emulsifier, and carrier solvent in skincare and personal care products.

Safety Precautions

Handle Propylene Glycol USP Grade in a well-ventilated area. While this product has a low toxicity profile, standard industrial hygiene practices should be observed. Wear appropriate Personal Protective Equipment (PPE), including chemical-resistant gloves and safety goggles, to prevent prolonged skin or eye contact. Store in cool, dry conditions in compatible containers such as HDPE or glass.

This product is not regulated as a hazardous material for transport (Non-Hazmat). However, always reference the Safety Data Sheet (SDS) for detailed spill response, first aid, and emergency procedures. In the event of exposure: rinse eyes cautiously with water; wash skin with soap and water; move to fresh air if inhaled. Verify compliance with all local, state, and federal regulations regarding storage and disposal.

Benefits

High Purity USP Grade: Meets USP-NF monograph requirements with >99.5% assay for critical applications.
Versatile Solvent: Miscible with water, acetone, and chloroform, supporting diverse industrial formulations.
Low Toxicity Profile: Suitable for applications where low toxicity and low volatility are required.
Reliable Supply Chain: Available in bulk sizes from 1 gallon to 330-gallon totes for scalable manufacturing.

Related Products

Property	Value
Molecular Weight	76.09 g/mol
Formula	C3H8O2
Assay	100%%
Grade	USP
Flash Point	104
Form	Liquid
Solubility	High water solubility
Appearance	Transparent, mobile, colorless glycol liquid
Melting Point	-59 °C
Boiling Point	188 °C
Industry	Medical, Cosmetic, Personal Care, Research, Datacenter , HVAC , Research , Automotive

Frequently Asked Questions About Propylene Glycol USP Grade

What is Propylene Glycol USP Grade and what is its chemical formula?

Propylene Glycol USP Grade is a chemical compound with the molecular formula C3H8O2, registered under CAS Number 57-55-6 by the Chemical Abstracts Service (PubChem), with a molecular weight of 76.09 g/mol. Alliance Chemical supplies Propylene Glycol USP Grade in USP grade for laboratory, industrial, and commercial applications.

What are the physical properties of Propylene Glycol USP Grade?

According to the NIOSH Pocket Guide to Chemical Hazards, Propylene Glycol USP Grade is supplied as a transparent, mobile, colorless glycol liquid. It has a melting point of -59°C, a boiling point of 188°C, a flash point of 104. Solubility: High water solubility.

What grade and purity of Propylene Glycol USP Grade does Alliance Chemical offer?

Alliance Chemical offers Propylene Glycol USP Grade in USP grade with a purity assay of 100%. Every lot ships with a Certificate of Analysis (COA) and Safety Data Sheet (SDS) prepared in accordance with OSHA Hazard Communication Standard 29 CFR 1910.1200 and GHS Revision 7. Download SDS.

What are common industrial applications of Propylene Glycol USP Grade?

Propylene Glycol USP Grade serves a wide range of sectors, including Medical, Cosmetic, Personal Care, Research, Datacenter, and HVAC, among others.Alliance Chemical provides the documentation and quality certifications required for use in regulated environments.

What PPE is required when handling Propylene Glycol USP Grade?

OSHA-mandated PPE per 29 CFR 1910.132-138:Nitrile gloves (8+ mil), safety goggles, flame-resistant clothing, grounded footwear, closed-toe chemical-resistant footwear. Respiratory protection (organic vapor cartridge) required in areas exceeding PEL/TLV per 29 CFR 1910.134. Emergency eyewash station and safety shower must be accessible within 10 seconds per ANSI Z358.1. Consult the SDS available from Alliance Chemical for complete PPE requirements.

What are the storage requirements for Propylene Glycol USP Grade?

Store perOSHA 29 CFR 1910.106: Approved flammable storage cabinet, maximum 60 gallons per cabinet, grounding/bonding required. Temperature range:15-25°C. Segregate from:oxidizers, ignition sources. Maximum storage:2-3 years unopened.

What is the emergency spill procedure for Propylene Glycol USP Grade?

Emergency response per EPA SPCC (40 CFR 112) and OSHA 29 CFR 1910.120: (1) Alert personnel, evacuate area to 100 feet. (2) Eliminate ignition sources if flammable. (3) Don PPE per SDS Section 8. (4) Stop leak if safe; use emergency shutoffs. (5) Contain with non-combustible absorbent materials, dike with sand/earth. (6)Absorb with vermiculite or commercial spill kits. (7) Collect in DOT-approved containers, label as hazardous waste. Check 40 CFR 302.4 for Reportable Quantity. Emergency: Chemtel 1-800-255-3924 (24/7). Non-emergency: Alliance Chemical 512-365-6838.

What is the DOT shipping classification for Propylene Glycol USP Grade?

DOT Classification per 49 CFR 172.101:UN1993 (Flammable Liquid, N.O.S.), Hazard ClassNot Regulated, Packing GroupII/III. Requires: Hazmat shipping papers (49 CFR 172.200), UN specification packaging (49 CFR 173), hazmat labels (172.400). Alliance Chemical ships all orders in DOT-compliant packaging with proper documentation.

How must Propylene Glycol USP Grade waste be disposed?

Disposal per RCRA (40 CFR 261-265):Characteristic waste D001 (Ignitable, flash point <60°C). Generator requirements: EPA ID number required if >100 kg/month (40 CFR 262.12). Use EPA-permitted Treatment, Storage, Disposal Facility (TSDF). Never discharge to sewer without POTW written approval (40 CFR 403). Container disposal: Triple rinse (40 CFR 261.7), offer for reconditioning/recycling. State regulations may be more stringent — check with your local environmental agency. Consult the Alliance Chemical SDS for product-specific disposal guidance.

Does Alliance Chemical provide an SDS and COA for Propylene Glycol USP Grade?

Yes. Alliance Chemical provides a Safety Data Sheet (SDS) and Certificate of Analysis (COA) for every lot of Propylene Glycol USP Grade. The SDS is prepared in accordance with OSHA Hazard Communication Standard 29 CFR 1910.1200 and the Globally Harmonized System (GHS) Revision 7, covering all 16 required sections including hazard identification, first aid measures, firefighting measures, handling and storage, exposure controls, and regulatory information. The SDS is available for download directly from this product page. COAs are available upon request by contacting Alliance Chemical at 512-365-6838.