Propylene Glycol USP Grade

Category : Glycols

$26.45
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Other Grades & Concentrations

Available in other grades and concentrations:

CAS: 57-55-6 C3H8O2
Propylene Glycol 60% USP Grade
From $19.00
CAS: 57-55-6 C3H8O2
CAS: 57-55-6 50% C3H8O2 / 50% H2O
CAS: 57-55-6 C3H8O2
$26.45
Other Grades & Concentrations

Available in other grades and concentrations:

CAS: 57-55-6 C3H8O2
Propylene Glycol 60% USP Grade
From $19.00
CAS: 57-55-6 C3H8O2
CAS: 57-55-6 50% C3H8O2 / 50% H2O
CAS: 57-55-6 C3H8O2

Propylene Glycol USP Grade

$26.45

Commercial Fulfillment Snapshot

Buy Propylene Glycol USP Grade with faster decisions and fewer back-and-forth emails.

Ships from Taylor, Texas. In-stock orders placed before 1:00 PM CT (Mon-Thu) and before 12:00 PM CT (Fri) typically ship same business day. Order online 24/7.

Technical Documents

Lot-specific COA is issued per shipment batch.

Who Buys This
  • Pharmaceutical manufacturers
  • Medical device companies
  • Cosmetic formulators
  • Personal care manufacturers
  • Research laboratories
Purity / Grade Guide
  • USP pharmaceutical grade quality
  • Medical & cosmetic formulations
  • Regulated industry applications
  • COA confirms grade compliance
Pack Sizes
  • 1 Quart: lab & small jobs
  • 1 Gallon: shop & maintenance
  • 5 Gallon: production & regular use
  • 15 Gallon: mid-volume operations
  • 55 Gallon: bulk drum
  • 275 Gallon: high-volume tote
  • 330 Gallon: max-volume tote
SDS / COA / TDS
  • SDS safety documentation included
  • COA certificate of analysis
  • USP grade verification
  • Non-regulated ground shipment
Small Packs: UPS Ground nationwide for pints, quarts, and gallons.
LTL / FTL: ABF, SEFL, Saia, XPO, and partner carriers for pails, drums, totes, and full truckloads.
Support: Email or call for freight options, hazardous-material routing, and lead-time confirmation.

Why Propylene Glycol USP Grade

Propylene Glycol USP Grade at 100% concentration provides an uninhibited, entirely non-toxic heat transfer fluid and chemical intermediate engineered for operations requiring absolute safety compliance. Because this formulation arrives at full strength with zero added water or corrosion inhibitors, facility engineers can custom-dilute the transparent, colorless liquid to achieve the exact freeze protection curve required for their local climate zone. Diluting this 100% base allows operators to maximize specific heat capacity, as pure glycol transfers heat less efficiently than a balanced glycol-water mixture. For industries evaluating heat transfer options, this product delivers the critical food-safe advantage over highly toxic ethylene glycol, ensuring operational continuity in environments where incidental contact with consumables is a risk. With an initial flash point of 104°F and high water solubility, it integrates readily into existing aqueous systems.

Best Applications for This Grade

  • Commonly applied in food processing and beverage facility chillers, where engineers dilute the 100% concentrate to match their specific operating temperatures while maintaining strict USP compliance to protect against mechanical leak contamination.
  • Commonly applied in medical manufacturing and cosmetic formulation as a highly stable, water-soluble humectant and solvent, utilizing its colorless and mobile liquid properties to control moisture retention without altering the physical appearance of the final product.
  • Commonly applied in datacenter liquid cooling loops and specialized research laboratories where technicians demand a pure, uninhibited thermal fluid to manually formulate custom heat transfer mixtures without introducing heavy industrial corrosion inhibitors.
  • Commonly applied in specialized automotive and fleet maintenance environments where non-toxic fluids are mandated for specific cooling circuits, ensuring mechanic safety and environmental compliance compared to standard toxic ethylene mixtures.

When to Choose a Different Grade

  • If your facility requires a pre-mixed, food-safe solution ready for immediate deployment in mild climates without the labor and water-quality variables of on-site dilution, choose 30% Propylene Glycol USP Grade.
  • If you are managing industrial closed-loop HVAC systems or heavy-duty chillers with no risk of food contact, operations dictate an inhibited fluid to provide aggressive corrosion protection for internal copper, steel, and brass piping, rather than this uninhibited USP base.
  • If your facility operates in extreme freeze-prone regions and requires immediate top-off fluid, selecting a pre-diluted 40% or 50% concentration ensures stable freeze point depression without the risk of an improper on-site mixture ratio freezing and bursting system lines.
Property Value
Molecular Weight 76.09
Formula C3H8O2
Assay 99.5-100.5%
Grade USP Grade
Flash Point 104°C (219.2°F)
Form Liquid
Solubility Miscible with water, ethanol, and acetone
Appearance Clear, colorless liquid
Melting Point -59
Boiling Point 188.2
Specific Gravity 1.036
Industry Analytical Chemistry, Food Industry, Pharmaceutical, Industrial, Personal Care

Frequently Asked Questions About Propylene Glycol USP Grade

What is Propylene Glycol USP Grade and what is its chemical formula?
Propylene Glycol USP Grade is a chemical compound with the molecular formula C3H8O2, registered under CAS Number 57-55-6 by the Chemical Abstracts Service (PubChem), with a molecular weight of 76.09 g/mol. Alliance Chemical supplies Propylene Glycol USP Grade in USP grade for laboratory, industrial, and commercial applications.
What are the physical properties of Propylene Glycol USP Grade?
According to the NIOSH Pocket Guide to Chemical Hazards, Propylene Glycol USP Grade is supplied as a transparent, mobile, colorless glycol liquid. It has a melting point of -59°C (-74.2°F)°C, a boiling point of 188°C (370.4°F)°C, a flash point of 104°C (219.2°F). Solubility: High water solubility.
What grade and purity of Propylene Glycol USP Grade does Alliance Chemical offer?
Alliance Chemical offers Propylene Glycol USP Grade in USP grade with a purity assay of 100%. Every lot ships with a Certificate of Analysis (COA) and Safety Data Sheet (SDS) prepared in accordance with OSHA Hazard Communication Standard 29 CFR 1910.1200 and GHS Revision 7. Download SDS.
What are common industrial applications of Propylene Glycol USP Grade?
Propylene Glycol USP Grade serves a wide range of sectors, including Cosmetics & Personal Care, HVAC & Cooling, Healthcare & Pharma, Industrial & Manufacturing, and Lab & Research.Alliance Chemical provides the documentation and quality certifications required for use in regulated environments.
What PPE is required when handling Propylene Glycol USP Grade?
OSHA-mandated PPE per 29 CFR 1910.132-138:Nitrile gloves (8+ mil), safety goggles, flame-resistant clothing, grounded footwear, closed-toe chemical-resistant footwear. Respiratory protection (organic vapor cartridge) required in areas exceeding PEL/TLV per 29 CFR 1910.134. Emergency eyewash station and safety shower must be accessible within 10 seconds per ANSI Z358.1. Consult the SDS available from Alliance Chemical for complete PPE requirements.
What are the storage requirements for Propylene Glycol USP Grade?
Store perOSHA 29 CFR 1910.106: Approved flammable storage cabinet, maximum 60 gallons per cabinet, grounding/bonding required. Temperature range:15-25°C. Segregate from:oxidizers, ignition sources. Maximum storage:2-3 years unopened.
What is the emergency spill procedure for Propylene Glycol USP Grade?
Emergency response per EPA SPCC (40 CFR 112) and OSHA 29 CFR 1910.120: (1) Alert personnel, evacuate area to 100 feet. (2) Eliminate ignition sources if flammable. (3) Don PPE per SDS Section 8. (4) Stop leak if safe; use emergency shutoffs. (5) Contain with non-combustible absorbent materials, dike with sand/earth. (6)Absorb with vermiculite or commercial spill kits. (7) Collect in DOT-approved containers, label as hazardous waste. Check 40 CFR 302.4 for Reportable Quantity. Emergency: Chemtel 1-800-255-3924 (24/7). Non-emergency: Alliance Chemical 512-365-6838.
What is the DOT shipping classification for Propylene Glycol USP Grade?
DOT Classification per 49 CFR 172.101:UN1993 (Flammable Liquid, N.O.S.), Hazard ClassNot Regulated, Packing GroupII/III. Requires: Hazmat shipping papers (49 CFR 172.200), UN specification packaging (49 CFR 173), hazmat labels (172.400). Alliance Chemical ships all orders in DOT-compliant packaging with proper documentation.
How must Propylene Glycol USP Grade waste be disposed?
Disposal per RCRA (40 CFR 261-265):Characteristic waste D001 (Ignitable, flash point <60°C). Generator requirements: EPA ID number required if >100 kg/month (40 CFR 262.12). Use EPA-permitted Treatment, Storage, Disposal Facility (TSDF). Never discharge to sewer without POTW written approval (40 CFR 403). Container disposal: Triple rinse (40 CFR 261.7), offer for reconditioning/recycling. State regulations may be more stringent — check with your local environmental agency. Consult the Alliance Chemical SDS for product-specific disposal guidance.
Does Alliance Chemical provide an SDS and COA for Propylene Glycol USP Grade?
Yes. Alliance Chemical provides a Safety Data Sheet (SDS) and Certificate of Analysis (COA) for every lot of Propylene Glycol USP Grade. The SDS is prepared in accordance with OSHA Hazard Communication Standard 29 CFR 1910.1200 and the Globally Harmonized System (GHS) Revision 7, covering all 16 required sections including hazard identification, first aid measures, firefighting measures, handling and storage, exposure controls, and regulatory information. The SDS is available for download directly from this product page. COAs are available upon request by contacting Alliance Chemical at 512-365-6838.