Propylene Glycol 50% – USP Grade (C3H8O2)

Category : Glycols

$18.52
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Other Grades & Concentrations

Available in other grades and concentrations:

CAS: 57-55-6 C3H8O2
Propylene Glycol USP Grade
From $26.45
CAS: 57-55-6 C3H8O2
Propylene Glycol 60% USP Grade
From $19.00
CAS: 57-55-6 C3H8O2
CAS: 57-55-6 C3H8O2
$18.52
Other Grades & Concentrations

Available in other grades and concentrations:

CAS: 57-55-6 C3H8O2
Propylene Glycol USP Grade
From $26.45
CAS: 57-55-6 C3H8O2
Propylene Glycol 60% USP Grade
From $19.00
CAS: 57-55-6 C3H8O2
CAS: 57-55-6 C3H8O2

Propylene Glycol 50% – USP Grade (C3H8O2)

$18.52

Commercial Fulfillment Snapshot

Buy Propylene Glycol 50% – USP Grade (C3H8O2) with faster decisions and fewer back-and-forth emails.

Ships from Taylor, Texas. In-stock orders placed before 1:00 PM CT (Mon-Thu) and before 12:00 PM CT (Fri) typically ship same business day. Order online 24/7.

Technical Documents

Lot-specific COA is issued per shipment batch.

Who Buys This
  • Pharmaceutical manufacturers
  • Food processing facilities
  • HVAC system contractors
  • Medical device companies
  • Data center cooling operators
Purity / Grade Guide
  • USP grade pharmaceutical applications
  • 50% propylene glycol concentration
  • Food & medical grade uses
  • Low toxicity safety profile
Pack Sizes
  • 1 Quart: lab & small jobs
  • 1 Gallon: shop & maintenance
  • 5 Gallon: production & regular use
  • 15 Gallon: mid-volume operations
  • 55 Gallon: bulk drum
  • 275 Gallon: high-volume tote
  • 330 Gallon: max-volume tote
SDS / COA / TDS
  • SDS included with order
  • COA
  • Non-regulated ground shipment
  • USP certification documentation
Small Packs: UPS Ground nationwide for pints, quarts, and gallons.
LTL / FTL: ABF, SEFL, Saia, XPO, and partner carriers for pails, drums, totes, and full truckloads.
Support: Email or call for freight options, hazardous-material routing, and lead-time confirmation.

Why Propylene Glycol 50% – USP Grade

Propylene Glycol 50% – USP Grade is a non-flammable, uninhibited heat transfer fluid pre-mixed at a precise 50% C3H8O2 to 50% H2O ratio, delivering freeze protection down to approximately -30°F (-34°C). HVAC contractors and plant engineers select this specific concentration to maintain reliable thermal regulation in severe winter climates while completely avoiding the toxicity risks inherent to ethylene glycol. Because it strictly adheres to USP purity standards, this clear, colorless liquid contains no added chemical corrosion inhibitors. This unadulterated composition is necessary for closed-loop chilling systems where maintaining a non-toxic, food-safe environment is a non-negotiable operational requirement.

Best Applications for This Grade

  • Food Processing and Beverage Plants: Commonly applied in secondary cooling loops, fermentation tank jackets, and dairy chilling lines where non-toxic fluids guarantee safety in the event of an accidental leak or incidental food contact.
  • Pharmaceutical and Medical Manufacturing: Pumped through jacketed reactors and specialized climate-control systems, satisfying strict regulatory demands by avoiding heavy metal inhibitors while regulating exact batch temperatures.
  • Datacenter and AI Infrastructure: Commonly applied in liquid cooling manifolds and server rack heat exchangers, providing the stable thermal conductivity necessary to safeguard high-density computing hardware from thermal throttling.
  • Commercial HVAC and Solar Thermal: Circulated in exterior rooftop chillers and solar collector arrays subjected to harsh freezes, preventing catastrophic pipe bursts while remaining environmentally benign.
  • Cold Storage and Refrigeration: Utilized under facility floors and in massive refrigeration coils to maintain deep sub-zero operational temperatures without pushing the circulation pumps beyond their viscosity limits.

When to Choose a Different Grade

  • If your facility operates in a milder geographic region where extreme sub-zero burst protection is unnecessary, and your pumps require the increased heat transfer efficiency of a lower-viscosity fluid, choose 30% Propylene Glycol USP Grade.
  • If your closed-loop system is constructed of mixed metals (such as copper, brass, and cast iron) and requires aggressive chemical corrosion inhibitors—and it strictly operates outside of any food, pharmaceutical, or medical environment—you will require an inhibited technical grade fluid rather than this uninhibited USP solution.
  • If your operational protocols dictate diluting heat transfer fluids on-site to hit custom freeze protection benchmarks, rather than relying on a pre-mixed 50% solution, sourcing a 100% USP glycol concentrate—which is completely miscible with water—is required for custom blending.
Property Value
Molecular Weight 76.09
Formula 50% C3H8O2 / 50% H2O
Assay 99-100.5%
Grade USP Grade
Flash Point Non-flammable
Form Liquid
Solubility Miscible with water and many organic solvents
Appearance Clear, colorless liquid
Melting Point -59
Boiling Point 188.2
Specific Gravity 1.036
Industry Analytical Chemistry, Food Industry, Pharmaceutical, Industrial, Personal Care

Frequently Asked Questions About Propylene Glycol 50% – USP Grade (C3H8O2)

What is Propylene Glycol 50% – USP Grade (C3H8O2) and what is its chemical formula?
Propylene Glycol 50% – USP Grade (C3H8O2) is a chemical compound with the molecular formula 50% C3H8O2 / 50% H2O, registered under CAS Number 57-55-6 by the Chemical Abstracts Service (PubChem), with a molecular weight of 76.09 (propylene glycol component) g/mol. Alliance Chemical supplies Propylene Glycol 50% – USP Grade (C3H8O2) in USP grade for laboratory, industrial, and commercial applications.
What are the physical properties of Propylene Glycol 50% – USP Grade (C3H8O2)?
According to the NIOSH Pocket Guide to Chemical Hazards, Propylene Glycol 50% – USP Grade (C3H8O2) has a clear, colorless liquid appearance. It has a melting point of -32°C (-25.6°F)°C, a boiling point of ~106°C, a flash point of Non-flammable. The specific gravity is 1.04 relative to water. Solubility: Completely miscible with water.
What grade and purity of Propylene Glycol 50% – USP Grade (C3H8O2) does Alliance Chemical offer?
Alliance Chemical offers Propylene Glycol 50% – USP Grade (C3H8O2) in USP grade with a purity assay of 50 Propylene Glycol%. Every lot ships with a Certificate of Analysis (COA) and Safety Data Sheet (SDS) prepared in accordance with OSHA Hazard Communication Standard 29 CFR 1910.1200 and GHS Revision 7. Download SDS.
What are common industrial applications of Propylene Glycol 50% – USP Grade (C3H8O2)?
Propylene Glycol 50% – USP Grade (C3H8O2) serves a wide range of sectors, including Food & Agriculture, HVAC & Cooling, Healthcare & Pharma, and Industrial & Manufacturing.Alliance Chemical provides the documentation and quality certifications required for use in regulated environments.
What PPE is required when handling Propylene Glycol 50% – USP Grade (C3H8O2)?
OSHA-mandated PPE per 29 CFR 1910.132-138:Nitrile gloves (8+ mil), safety goggles, flame-resistant clothing, grounded footwear, closed-toe chemical-resistant footwear. Respiratory protection (organic vapor cartridge) required in areas exceeding PEL/TLV per 29 CFR 1910.134. Emergency eyewash station and safety shower must be accessible within 10 seconds per ANSI Z358.1. Consult the SDS available from Alliance Chemical for complete PPE requirements.
What are the storage requirements for Propylene Glycol 50% – USP Grade (C3H8O2)?
Store perOSHA 29 CFR 1910.106: Approved flammable storage cabinet, maximum 60 gallons per cabinet, grounding/bonding required. Temperature range:15-25°C. Segregate from:oxidizers, ignition sources. Maximum storage:2-3 years unopened.
What is the emergency spill procedure for Propylene Glycol 50% – USP Grade (C3H8O2)?
Emergency response per EPA SPCC (40 CFR 112) and OSHA 29 CFR 1910.120: (1) Alert personnel, evacuate area to 100 feet. (2) Eliminate ignition sources if flammable. (3) Don PPE per SDS Section 8. (4) Stop leak if safe; use emergency shutoffs. (5) Contain with non-combustible absorbent materials, dike with sand/earth. (6)Absorb with vermiculite or commercial spill kits. (7) Collect in DOT-approved containers, label as hazardous waste. Check 40 CFR 302.4 for Reportable Quantity. Emergency: Chemtel 1-800-255-3924 (24/7). Non-emergency: Alliance Chemical 512-365-6838.
What is the DOT shipping classification for Propylene Glycol 50% – USP Grade (C3H8O2)?
DOT Classification per 49 CFR 172.101:UN1993 (Flammable Liquid, N.O.S.), Hazard Class3 (Flammable), Packing GroupII/III. Requires: Hazmat shipping papers (49 CFR 172.200), UN specification packaging (49 CFR 173), hazmat labels (172.400). Alliance Chemical ships all orders in DOT-compliant packaging with proper documentation.
How must Propylene Glycol 50% – USP Grade (C3H8O2) waste be disposed?
Disposal per RCRA (40 CFR 261-265):Characteristic waste D001 (Ignitable, flash point <60°C). Generator requirements: EPA ID number required if >100 kg/month (40 CFR 262.12). Use EPA-permitted Treatment, Storage, Disposal Facility (TSDF). Never discharge to sewer without POTW written approval (40 CFR 403). Container disposal: Triple rinse (40 CFR 261.7), offer for reconditioning/recycling. State regulations may be more stringent — check with your local environmental agency. Consult the Alliance Chemical SDS for product-specific disposal guidance.
Does Alliance Chemical provide an SDS and COA for Propylene Glycol 50% – USP Grade (C3H8O2)?
Yes. Alliance Chemical provides a Safety Data Sheet (SDS) and Certificate of Analysis (COA) for every lot of Propylene Glycol 50% – USP Grade (C3H8O2). The SDS is prepared in accordance with OSHA Hazard Communication Standard 29 CFR 1910.1200 and the Globally Harmonized System (GHS) Revision 7, covering all 16 required sections including hazard identification, first aid measures, firefighting measures, handling and storage, exposure controls, and regulatory information. The SDS is available for download directly from this product page. COAs are available upon request by contacting Alliance Chemical at 512-365-6838.