Trisodium Phosphate Dodecahydrate - ACS Reagent Grade

Product Overview

Trisodium Phosphate Dodecahydrate (Na3PO4·12H2O) is a highly soluble crystalline reagent-grade compound widely used as a buffering agent and pH adjuster in diverse aqueous systems. In ACS Reagent Grade, it meets stringent purity criteria suitable for analytical and preparative work. Its thermal stability and predictable solubility profile enable precise dosing in laboratory, industrial cleaning, and process-control applications. The material is supplied as a white crystalline powder with an odorless profile, designed for dry storage to preserve performance and minimize clumping during handling.

As a versatile alkali source, it supports buffering in phosphate systems, acts to raise pH in cleaning formulations, and contributes to hardness adjustment in water treatment processes. Its low heavy metals content and compliance with ACS Reagent Grade and USP-NF monographs provide assurance for quality-critical workflows in analytical laboratories, food processing, and environmental applications. The product is characterized by controlled assay, low chloride and nitrate contaminants, and low levels of trace metals, enabling reliable repeatability in high-precision experiments and routine industrial operations.

Key Properties

• Appearance: White crystalline powder
• Odor: Odorless
• CAS: 10101-89-0
• Chemical Formula: Na₃PO₄·12H₂O
• Molecular Weight: 380.12 g/mol
• Solubility: Soluble in water
• Specific Gravity (20°C): 1.63 (typical)
• Residue After Ignition: Max 0.1 wt% (typical 0.05)
• Chloride (Cl⁻): Max 0.5 ppm (typical 0.2)
• Nitrate (NO₃⁻): Max 50 ppm (typical 20)
• Ammonium (NH₄⁺): Max 10 ppm (typical 2)
• Sulfate (SO₄²⁻): Max 150 ppm (typical 50)
• Phosphate (PO₄³⁻): Max 2000 ppm (typical 600)
• Arsenic (As): Max 0.05 ppm (typical 0.02)
• Heavy Metals (as Pb): Max 0.5 ppm (typical 0.1)
• Iron (Fe): Max 0.2 ppm (typical 0.05)
• Copper (Cu): Max 0.2 ppm (typical 0.05)
• Manganese (Mn): Max 0.5 ppm (typical 0.1)
• Nickel (Ni): Max 0.2 ppm (typical 0.05)
• Chlorate (ClO₃⁻): Max 0.5 ppm (typical 0.1)
• Bromate (BrO₃⁻): Max 0.5 ppm (typical 0.1)
• Sodium (Na): Max 1000 ppm (typical 400)
• Potassium (K): Max 1000 ppm (typical 400)
• Magnesium (Mg): Max 1000 ppm (typical 400)
• Calcium (Ca): Max 1000 ppm (typical 400)
• Water Content: Max 0.5 wt% (typical 0.2)
• pH (1% solution or specified): Not provided here; reference product SDS for exact value in solution

Common Applications

• Application Category: Buffering Agent – Used to maintain stable pH in analytical reactions and sample preparation workflows, ensuring reproducible titrations and colorimetric assays in Analytical Chemistry.
• Application Category: Cleaning Agent – Alkaline cleaner for removal of grease, oils, and residues on industrial equipment and surfaces, leveraging its buffering capacity to sustain cleaning efficacy.
• Application Category: Food Additive – Acts as an emulsifier and stabilizer in selected food systems where phosphate buffering helps maintain texture and crystal stability, in accordance with regulatory guidelines.
• Application Category: Water Treatment – pH adjustment and hardness management in municipal and industrial water systems, contributing to preventing scale formation and optimizing downstream processes.
• Application Category: Laboratory Reagent – Standard reagent for calibration, dissolution, and solution preparation in research laboratories and educational facilities.

Safety Precautions

Handle with appropriate PPE including chemical-resistant gloves, safety goggles, and a lab coat. Store in a cool, dry place in HDPE or glass containers, away from moisture and incompatible substances. Use good ventilation to minimize inhalation of any powdered dust; avoid generating aerosols or dust clouds during transfer and weighing.

In case of exposure, follow standard SDS-directed procedures: eyewash stations for eye exposure, wash skin with soap and water, and seek medical attention for prolonged symptoms. In the event of a spill, sweep up carefully to avoid dust dispersion and place in sealed containers for proper disposal according to local regulations. Ensure containers are properly labeled and never mix with incompatible materials such as strong acids or bases in open systems.

Benefits

✔ ACS Reagent Grade quality – Meets high-purity standards suitable for analytical labs and regulated processes.
✔ High assay purity – Typical assay ~99.6% with strict lot-to-lot consistency for reliable dosing.
✔ Low trace metal content – Ensures suitability for pharmaceutical, food processing, and sensitive analyses.
✔ Comprehensive purity specification – Low chlorides, nitrates, sulfates, and heavy metals as validated by ICP-OES/ICP-MS methods.