Ethyl Acetate ACS

Product Overview

Ethyl Acetate ACS is a colorless, volatile liquid with a characteristic sweet, fruity odor and a widely recognized role as a high-purity solvent in analytical, industrial, and food-grade applications. With an ACS grade specification and an assay range of 99–100.5 wt%, it provides exceptional solvency for a broad spectrum of organics, including esters, alcohols, ketones, and resins. The product exhibits favorable physical properties for chromatographic and coating processes, including a low boiling point of 77–78°C, a relatively low viscosity, and favorable vapor pressure, enabling efficient evaporation and rapid drying in formulations and sample preparation workflows. The material is suitable for use in HPLC mobile phases, coatings, extractions, and cleaning applications where purity and consistency are required.

Ethyl Acetate ACS is produced and tested to rigorous standards, including trace metal analysis and low aldehyde content, to minimize impact on sensitive analytical methods and product formulations. Its compatibility with common solvents such as ethanol, ether, and chloroform makes it a versatile match for laboratory and manufacturing environments, while its favorable safety and storage characteristics support use under appropriate containment and handling practices.

Key Properties

• Assay (wt %): min 99 – max 100.5 (typical 99.8)
• Chemical Formula: C₄H₈O₂
• Molecular Weight: 88.11 g/mol
• Boiling Point: 77–78°C
• Specific Gravity (20°C): 0.895–0.902 (typical 0.899)
• Water Content: max 0.05 wt% (typical 0.02)
• Iron: max 0.2 ppm (typical 0.05)
• Color (APHA/Hazen): max 5 (typical 3)
• Heavy Metals: max 0.5 ppm (typical 0.1)
• Residue on Evaporation: max 0.001 wt% (typical 0.0005)
• Acidity (meq/g): max 0.0003 (typical 0.00015)
• Aldehydes: max 10 ppm (typical 4)
• Arsenic (As): max 0.5 ppm (typical 0.1)
• Lead (Pb): max 0.2 ppm (typical 0.05)
• Zinc (Zn): max 0.5 ppm (typical 0.1)
• Copper (Cu): max 0.2 ppm (typical 0.05)
• Manganese (Mn): max 0.2 ppm (typical 0.05)
• Nickel (Ni): max 0.2 ppm (typical 0.05)
• Calcium (Ca): max 2 ppm (typical 0.5)
• Magnesium (Mg): max 2 ppm (typical 0.5)
• Potassium (K): max 2 ppm (typical 0.5)
• Sodium (Na): max 2 ppm (typical 0.5)
• Aluminum (Al): max 0.5 ppm (typical 0.1)
• Chromium (Cr): max 0.5 ppm (typical 0.1)
• Cobalt (Co): max 0.2 ppm (typical 0.05)

Common Applications

• Application Category: HPLC Mobile Phase – Used as a component in reversed-phase mobile phases for separating organic compounds with good solvent strength and volatility that supports rapid gradient elution and clean baseline performance.
• Application Category: Solvent for Coatings – Formulation solvent for paints, coatings, and adhesives, offering balanced evaporation rate and solvency for binders and pigments.
• Application Category: Extraction Solvent – Employed in extraction and purification processes for active pharmaceutical ingredients due to high purity and compatibility with many APIs.
• Application Category: Cleaning Agent – Effective removal of residues and contaminants from surfaces and process equipment in manufacturing environments.
• Application Category: Flavoring Agent – Utilized in food and beverage applications for its fruity aroma, meeting appropriate food-grade quality standards.

Safety Precautions

Handle Ethyl Acetate ACS in a well-ventilated area, away from heat, sparks, and open flames. Store in cool, ventilated spaces using containers made of HDPE or glass, with containers tightly closed when not in use to minimize evaporation. Use appropriate PPE, such as chemical-resistant gloves and splash goggles, and ensure proper grounding and ventilation in work areas to prevent accumulation of vapors. Follow compatible storage practices and segregate from oxidizing agents and strong acids to prevent exothermic interactions.

Immediate measures include using standard fire response protocols for flammable liquids, controlling vapors with good ventilation, and employing eyewash stations and emergency showers. In case of exposure, follow SDS guidance: for eyes—rinse cautiously with water for several minutes; for skin—wash with soap and water; for inhalation—move to fresh air and seek medical attention if symptoms persist; for ingestion—rinse mouth and do not induce vomiting, seeking medical advice as needed.

Benefits

✔ High Purity ACS Grade – Meets ACS and USP-NF monograph expectations with stringent impurity controls to minimize analytical interference.
✔ Wide Solvency and Volatility Range – Excellent solvency for organic compounds with rapid evaporation suitable for coatings, extractions, and chromatographic applications.