Isobutyl Alcohol 99%

Product Overview

Isobutyl Alcohol 99% is a colorless, flammable liquid with a characteristic alcohol odor (C₄H₁₀O). This high-purity solvent (ACS Reagent Grade; USP-NF Monograph compliant) is widely used as a versatile solvent and chemical intermediate in the production of esters, plasticizers, and analytical reagents. Typical assay is 99.5% with a confirmed reagent-grade profile when titrated against standardized NaOH, ensuring consistent solvent strength for demanding chromatographic and synthetic applications. Its miscibility with water and a broad range of organic solvents makes it an ideal component in HPLC mobile phases, coatings, and extraction processes while maintaining low acidity and minimal impurities that could affect analytical baselines and product integrity.

Expanded compatibility with common industrial processes is supported by stringent impurity controls, including low aldehydes (<10 ppm, typical 3 ppm), controlled chloride (<2 ppm, typical 1 ppm), and trace metals within tight limits. The material demonstrates robust storage stability under inert atmosphere, with a long shelf life of up to 24 months when stored properly. It is suitable for use in analytical and manufacturing environments requiring high purity solvents with precise composition verification through rapid quality control parameters such as refractive index (1.396 at 20°C) and specific gravity, enabling reproducible results across batches.

Key Properties

• Property Name: Isobutyl Alcohol (2-Methyl-1-propanol)
• Chemical Formula: C₄H₁₀O
• Molecular Weight: 74.12 g/mol
• Boiling Point: 108–110°C
• Specific Gravity: 0.803 g/mL at 25°C
• Density (25°C): 0.803 g/mL
• Flash Point: 11°C (52°F)
• Vapor Pressure (20°C): 20 mmHg
• Refractive Index (20°C): 1.396
• Viscosity (25°C): 0.54 cP
• Water Content: < 0.05 wt% (typical 0.02)
• Assay (wt%): 99–100 (typical 99.5) by Titration with standardized NaOH
• Aldehydes: < 10 ppm (typical 3 ppm) by GC with derivatization
• Chloride (Cl⁻): < 2 ppm (typical 1 ppm) by IC
• Arsenic (As): < 0.5 ppm (typical 0.2 ppm) by ICP-MS
• Heavy Metals (as Pb): < 0.5 ppm (typical 0.1 ppm) by ICP-MS
• Storage Type: Inert atmosphere recommended; HDPE or glass containers advised

Common Applications

• HPLC Mobile Phase: Commonly used as a mobile phase component in reversed-phase high-performance liquid chromatography for separating organic compounds.
• Solvent for Paints and Coatings: Utilized as a solvent in the formulation of paints and coatings due to its excellent solvency properties.
• Intermediate in Chemical Synthesis: Serves as a key intermediate in the production of various chemicals, including esters and plasticizers.
• Extraction Solvent: Used in extraction processes for isolating active pharmaceutical ingredients.
• Cleaning Agent: Effective as a cleaning agent in various industrial applications due to its solvent properties.

Safety Precautions

Handle in a well-ventilated area away from ignition sources. Store in a cool, ventilated location in containers made of HDPE or glass, away from heat, direct sunlight, and incompatible oxidizers or acids. Use appropriate PPE including chemical-resistant gloves and splash goggles. Ensure proper grounding and bonding to prevent static discharge during handling and transfer. Maintain container sealed when not in use to minimize vapor exposure and evaporation risks.

Avoid inhalation, ingestion, and prolonged skin or eye contact. In case of exposure, follow established emergency procedures per the Safety Data Sheet (SDS): evacuate the area for inhalation exposure, flush eyes/skin with water for at least 15 minutes if contact occurs, and seek medical attention for any signs of irritation, dizziness, or respiratory distress. In the event of a spill, contain and collect material using inert absorbents and dispose of as hazardous waste in accordance with local regulations. Transport as UN 1219, Isobutanol, Class 3, Packing Group II.

Benefits

✔ High Purity ACS/USP-NF Compliance – Reliable batch-to-batch composition with strict impurity controls ensuring analytical reproducibility and product integrity.
✔ Excellent Solvency – Broad compatibility with water and organic solvents makes it a versatile solvent for coatings, extractions, and synthesis.
✔ Stability and Handling Consistency – Low acidity and controlled aldehyde/metal impurities minimize baseline drift in HPLC and maintain solvent performance over shelf life.