Xylene ACS Grade

Product Overview

Xylene ACS Grade is a colorless, flammable liquid with a characteristic sweet, aromatic odor. This product is a mixture of the three isomers—ortho-, meta-, and para-xylene—forming a versatile solvent with well-defined physical properties suitable for analytical and industrial workflows. The ACS grade designation indicates a level of purity consistent with reagent chemicals used in laboratory and manufacturing environments, validated by GC with internal standards and aligned with ACS Reagent Grade and USP-NF monographs. With a boiling range of 137–144°C and a low water content, it provides robust solvency for a broad spectrum of organic substrates while maintaining compatibility with common containment materials such as HDPE and glass. The product’s refractive index (1.496 at 20°C) and density (~0.867 g/mL at 25°C) support precise method development in chromatographic and spectroscopic applications, including HPLC mobile phases and coating formulations. Safety data reflect its flammability (flash point 25°C) and appropriate handling requirements to protect personnel and equipment in process environments.

Its ACS grade quality, low trace metals, and controlled acidity (≤0.0003 meq/g) minimize catalyst poisoning and side reactions during synthesis and purification steps. The material is routinely stored under inert atmosphere or sealed conditions to prevent oxidative degradation, ensuring stable performance over the stated shelf life of 24 months when stored properly. Widely used in analytical chemistry, coatings, and chemical manufacturing, Xylene ACS Grade remains a dependable solvent for reversing-phase chromatography, paint and coating formulations, and as an intermediate in plastic and resin production. For safety and compliance, refer to the SDS and relevant standards (ACS, USP-NF) before use.

Key Properties

• Appearance: Clear, colorless liquid
• Odor: Sweet, aromatic odor
• Chemical Formula: C₈H₁₀
• Molecular Weight: 106.17 g/mol
• Boiling Point (range): 137–144°C
• Freezing Point: -47°C
• Solubility: Insoluble in water; soluble in organic solvents
• Flash Point: 25°C
• Vapor Pressure (20°C): 6.7 mmHg
• Specific Gravity (20°C): 0.862 (typical; range 0.86–0.865)
• Density (25°C): 0.867 g/mL
• Refractive Index (20°C): 1.496
• Molecular Formula: C₈H₁₀

Common Applications

• HPLC Mobile Phase: Used as a mobile phase component in reversed-phase HPLC to separate organic compounds with high solvency and compatibility with common stationary phases.
• Solvent for Paints and Coatings: Provides effective solvency for coatings, adhesives, and primers, supporting formulation stability and film formation.
• Chemical Intermediate: Serves as a precursor in the synthesis of plastics, resins, and synthetic fibers, enabling controlled reaction environments.
• Extraction Solvent (Pharmaceutical): Utilized in extraction processes for isolating active pharmaceutical ingredients from natural sources under controlled conditions.
• Cleaning Agent: Employed to remove grease and oil from industrial machinery and equipment, supporting maintenance and turnaround operations.

Safety Precautions

Store and handle Xylene ACS Grade in a cool, well-ventilated area away from heat sources and open flames. Use containers made of HDPE or glass to prevent interactions with container materials. Implement proper PPE, including chemical-resistant gloves and eye protection, and enforce strict no-smoking and ignition control in storage and handling zones. Ensure adequate ventilation to prevent vapor buildup and perform routine leak checks and fire risk assessments per applicable regulatory requirements.

Additional safety considerations include monitoring for exposure limits and implementing emergency procedures. The product is flammable (H226) and may be harmful if swallowed (H302) or cause serious eye irritation (H319). In case of exposure, follow SDS guidance: eyes—rinse with water; skin—wash with soap and water; inhalation—move to fresh air; ingestion—do not induce vomiting and seek medical attention. Transport is designated UN 1307, Xylene, Class 3, Packing Group III. Emergency responders should use appropriate PPE and ventilation to mitigate vapor hazards.

Benefits

✔ High Purity ACS Grade – Reliable reagent standard aligned with ACS and USP-NF requirements for consistent analytical performance.
✔ Broad Solvency – Excellent solvency for organic substrates, enabling flexible formulation and efficient reactions.
✔ Predictable Physical Properties – Narrow boiling range and well-defined density/refractive index support reproducible method development and quality control.