Propylene Glycol 50% – USP Grade (C3H8O2)

Product Overview

50% Propylene Glycol USP Grade is a pre-diluted heat transfer fluid consisting of 50% USP grade propylene glycol and 50% water, providing freeze protection to approximately -32°C (-26°F). This pharmaceutical-grade solution is designed for cold-climate applications requiring reliable freeze protection combined with low toxicity and food-safe characteristics. The pre-mixed formulation eliminates on-site dilution errors and ensures consistent performance across demanding industrial, datacenter, and manufacturing environments.

Each batch is manufactured to United States Pharmacopeia (USP) standards with complete quality documentation including Certificate of Analysis. The ready-to-use concentration simplifies installation and maintenance while providing the maximum freeze protection needed for facilities operating in cold weather regions with outdoor cooling equipment.

Key Properties

• Composition: 50% USP Grade Propylene Glycol (C3H8O2) / 50% Water
• CAS Number: 57-55-6 (propylene glycol component)
• Freeze Protection: Approximately -32°C (-26°F)
• Boiling Point: ~106°C
• Specific Gravity: ~1.04 at 20°C
• Flash Point: Non-flammable (diluted solution)
• Appearance: Clear, colorless liquid
• Solubility: Completely miscible with water
• pH: Neutral (~7.0)
• Viscosity: Low viscosity for efficient pumping
• Thermal Stability: Excellent stability across operating temperature ranges

Common Applications

• Datacenter Cooling Infrastructure: Critical coolant for liquid cooling systems in enterprise datacenters and hyperscale facilities located in cold climate regions. The 50% concentration provides enhanced freeze protection for outdoor cooling equipment including dry coolers, rooftop chillers, and heat rejection systems exposed to sub-zero temperatures. Particularly important for Northern facilities where outdoor ambient temperatures regularly drop well below freezing during winter months. The low toxicity and thermal efficiency make it suitable for mission-critical operations requiring year-round reliability.
• AI and High-Performance Computing: Essential cooling medium for AI training clusters, GPU farms, and high-density computing systems generating extreme heat loads. The higher glycol concentration ensures reliable operation in facilities with outdoor equipment while maintaining compatibility with precision cooling systems including direct-to-chip cold plates and immersion cooling infrastructure. Used in large-scale computing facilities where outdoor heat rejection equipment must operate through harsh winter conditions.
• Cold Climate HVAC Systems: Ready-to-use coolant for heating, ventilation, and air conditioning systems in commercial buildings, hospitals, and institutional facilities operating in cold weather regions. Provides superior freeze protection for outdoor condensing units, cooling towers, exposed piping, and rooftop equipment subject to freezing temperatures. The 50% concentration represents optimal freeze protection for systems in regions experiencing harsh winters with sustained sub-zero temperatures.
• Food Processing and Cold Storage: Food-safe heat transfer fluid for refrigeration systems, cold storage warehouses, freezer facilities, and food manufacturing plants requiring maximum freeze protection. The USP grade formulation and low toxicity ensure compliance with food safety requirements while providing reliable performance in facilities with outdoor refrigeration equipment and cold rooms operating in freezing climates.
• Pharmaceutical Manufacturing: Pre-diluted coolant for pharmaceutical production equipment, process cooling systems, and facility HVAC in cold climate pharmaceutical manufacturing plants. The pharmaceutical-grade purity and enhanced freeze protection make it suitable for cleanroom environments and regulated manufacturing facilities with outdoor cooling infrastructure.
• Industrial Process Cooling: Heat transfer medium for manufacturing equipment, injection molding machines, laser cutting systems, and industrial chillers in cold climate manufacturing facilities. The ready-to-use formulation provides maximum freeze protection for plants with outdoor cooling equipment, eliminating concerns about seasonal freeze damage to expensive industrial cooling systems.
• Solar Thermal and Renewable Energy: Freeze-protected heat transfer fluid for solar thermal collectors, geothermal systems, and renewable energy installations in cold climate zones. The 50% concentration provides maximum seasonal protection for systems with outdoor exposure while maintaining efficient thermal transfer properties throughout the year.
• Medical and Laboratory Facilities: Cooling fluid for laboratory freezers, medical imaging equipment, pharmaceutical refrigeration, and research equipment in facilities with outdoor cooling components. The low toxicity and pharmaceutical-grade quality make it appropriate for healthcare and research environments requiring both freeze protection and chemical purity.
• Snow Melt and Hydronic Systems: Antifreeze protection for radiant snow melt systems, heated driveways, outdoor hydronic heating, and building envelope systems in cold climate regions. The 50% concentration ensures reliable freeze protection for systems continuously exposed to winter weather conditions.

Safety Precautions

Use appropriate personal protective equipment including chemical-resistant gloves and safety glasses when handling. Ensure adequate ventilation in enclosed work areas. Store in sealed containers away from direct sunlight and extreme temperatures, preferably between 5-30°C. Label all containers clearly to prevent accidental mixing with incompatible solutions or incorrect concentrations.

In case of skin contact, rinse thoroughly with water. For eye contact, flush immediately with water for at least 15 minutes and seek medical attention if irritation persists. While propylene glycol is considered low toxicity and generally recognized as safe, follow standard chemical handling practices. Never use in potable water systems unless specifically approved for such use. Dispose of used coolant according to local environmental regulations. Refer to Safety Data Sheet for complete handling and emergency response information.

Benefits

Pre-diluted 50% formulation provides maximum freeze protection to -32°C (-26°F), making it ideal for cold climate facilities with outdoor cooling equipment. The ready-to-use concentration eliminates field mixing errors, reduces installation time, and ensures consistent performance throughout the system. Factory mixing guarantees proper glycol-to-water ratio, preventing under-protection that can lead to freeze damage or over-concentration that reduces heat transfer efficiency.

USP grade purity makes this solution suitable for regulated industries including food processing, pharmaceutical manufacturing, and medical facilities where low toxicity and chemical purity are critical. The food-safe characteristics provide superior safety compared to ethylene glycol-based coolants, particularly important in facilities where accidental exposure or environmental release could impact food products or human health.

The 50% concentration represents the optimal balance for cold weather applications, providing maximum freeze protection while maintaining good thermal transfer properties and reasonable viscosity for efficient pumping. Lower operating costs compared to pure glycol while delivering superior freeze protection versus lower concentrations. The solution's compatibility with common materials including metals and elastomers simplifies system design and reduces maintenance concerns.

Complete quality documentation with every order supports regulatory compliance and quality assurance requirements. Technical support available for system design questions, concentration selection, and application-specific recommendations.