Propylene Glycol 40% – USP Grade (C3H8O2)

Product Overview

40% Propylene Glycol USP Grade is a pre-diluted heat transfer fluid consisting of 40% USP grade propylene glycol and 60% water, providing freeze protection to approximately -23°C (-10°F). This pharmaceutical-grade solution bridges the gap between moderate and cold climate applications, offering enhanced freeze protection while maintaining excellent thermal efficiency and low toxicity. The pre-mixed formulation eliminates on-site dilution errors and ensures consistent performance across datacenter, industrial, and manufacturing environments.

Each batch is manufactured to United States Pharmacopeia (USP) standards with complete quality documentation including Certificate of Analysis. This concentration is ideal for facilities in regions experiencing cold winters but not requiring the maximum freeze protection of higher concentrations, optimizing both cost-effectiveness and thermal performance.

Key Properties

• Composition: 40% USP Grade Propylene Glycol (C3H8O2) / 60% Water
• CAS Number: 57-55-6 (propylene glycol component)
• Freeze Protection: Approximately -23°C (-10°F)
• Boiling Point: ~104°C
• Specific Gravity: ~1.03 at 20°C
• Flash Point: Non-flammable (diluted solution)
• Appearance: Clear, colorless liquid
• Solubility: Completely miscible with water
• pH: Neutral (~7.0)
• Viscosity: Low viscosity for efficient pumping and heat transfer
• Thermal Stability: Excellent stability across operating temperature ranges

Common Applications

• Datacenter Cooling Infrastructure: Reliable coolant for liquid cooling systems in enterprise datacenters and hyperscale facilities in regions experiencing cold winters but moderate average temperatures. The 40% concentration provides enhanced freeze protection for outdoor cooling equipment including dry coolers, rooftop chillers, and adiabatic cooling systems while maintaining superior thermal efficiency compared to higher concentrations. Ideal for facilities in transitional climate zones where outdoor temperatures occasionally drop below freezing but sustained extreme cold is uncommon.
• AI and High-Performance Computing: Cooling medium for AI training clusters, GPU farms, and high-density computing infrastructure where outdoor heat rejection equipment requires freeze protection beyond standard 30% solutions. The balanced concentration ensures reliable year-round operation for facilities with outdoor cooling components while maximizing heat transfer efficiency for high-wattage processors and accelerators generating extreme thermal loads.
• HVAC and Building Systems: Ready-to-use coolant for heating, ventilation, and air conditioning systems in commercial buildings, hospitals, educational facilities, and institutional buildings in moderate to cold climate regions. Provides reliable freeze protection for outdoor equipment, rooftop units, cooling towers, and exposed piping while maintaining energy-efficient heat transfer. The 40% concentration suits buildings in climate zones experiencing winter lows between -10°F and -20°F.
• Food Processing Facilities: Food-safe heat transfer fluid for refrigeration systems, process cooling, and temperature control equipment in food manufacturing, beverage production, and cold storage facilities with outdoor cooling equipment. The USP grade formulation and low toxicity ensure compliance with food safety requirements while providing adequate freeze protection for facilities in regions with moderate winter conditions.
• Pharmaceutical Manufacturing: Pre-diluted coolant for pharmaceutical production equipment, process cooling systems, and cleanroom HVAC in pharmaceutical manufacturing plants requiring enhanced freeze protection. The pharmaceutical-grade purity combined with balanced freeze protection makes it suitable for regulated facilities with outdoor cooling infrastructure in moderate cold climates.
• Industrial Process Cooling: Heat transfer medium for manufacturing equipment, injection molding machines, CNC systems, laser cutting equipment, and industrial chillers requiring reliable freeze protection. The ready-to-use 40% formulation provides enhanced winter protection for facilities with outdoor cooling equipment while maintaining optimal viscosity for efficient pumping and energy consumption.
• Solar Thermal Systems: Freeze-protected heat transfer fluid for solar thermal collectors, radiant heating systems, and renewable energy installations in regions requiring enhanced freeze protection beyond 30% solutions. The balanced concentration provides reliable seasonal protection while maintaining efficient thermal transfer throughout the year.
• Medical and Laboratory Equipment: Cooling fluid for laboratory chillers, medical imaging equipment, pharmaceutical storage, and research equipment in healthcare and research facilities with outdoor cooling components. The USP grade quality and low toxicity make it appropriate for medical environments requiring both freeze protection and chemical purity.
• Hydronic Heating Systems: Antifreeze protection for radiant floor heating, baseboard heating, hydronic distribution networks, and building heating systems in regions experiencing cold but not extreme winter temperatures. The 40% concentration provides reliable freeze protection while maintaining energy-efficient heat transfer for residential and commercial hydronic systems.

Safety Precautions

Use appropriate personal protective equipment including chemical-resistant gloves and safety glasses when handling. Ensure adequate ventilation in enclosed work areas. Store in sealed containers away from direct sunlight and extreme temperatures, preferably between 5-30°C. Label all containers clearly to prevent accidental mixing with other concentrations or incompatible chemicals.

In case of skin contact, rinse thoroughly with water. For eye contact, flush immediately with water for at least 15 minutes and seek medical attention if irritation persists. While propylene glycol is considered low toxicity and generally recognized as safe, follow standard chemical handling practices. Dispose of used coolant according to local environmental regulations. Refer to Safety Data Sheet for complete handling and emergency response information.

Benefits

Pre-diluted 40% formulation provides enhanced freeze protection to -23°C (-10°F), making it ideal for facilities in moderate to cold climate regions. The ready-to-use concentration eliminates field mixing errors, reduces installation time, and ensures consistent performance throughout cooling systems. Factory mixing guarantees proper glycol-to-water ratio for optimal freeze protection and thermal efficiency.

USP grade purity makes this solution suitable for regulated industries including food processing, pharmaceutical manufacturing, and medical facilities where low toxicity and chemical purity are essential. The food-safe characteristics provide superior safety compared to ethylene glycol-based coolants, particularly important in applications where accidental exposure could impact food products or human health.

The 40% concentration strikes an optimal balance between enhanced freeze protection, cost-effectiveness, and thermal performance. Compared to 50% solutions, the lower glycol content reduces material costs and improves heat transfer efficiency while still providing substantial freeze protection for most cold climate applications. Lower viscosity compared to higher concentrations reduces pumping energy requirements and improves system efficiency.

Complete quality documentation with every order supports regulatory compliance and quality assurance programs. The balanced concentration simplifies system maintenance while providing reliable year-round operation in regions where outdoor equipment faces occasional freezing temperatures but not sustained extreme cold.